SHOX2 Overexpression Favors Differentiation of Embryonic Stem Cells into Cardiac Pacemaker Cells, Improving Biological Pacing Ability

When pluripotency factors are removed, embryonic stem cells (ESCs) undergo spontaneous differentiation, which, among other lineages, also gives rise to cardiac sublineages, including chamber cardiomyocytes and pacemaker cells. Such heterogeneity complicates the use of ESC-derived heart cells in ther...

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Detalles Bibliográficos
Autores principales: Ionta, Vittoria, Liang, Wenbin, Kim, Elizabeth H., Rafie, Reza, Giacomello, Alessandro, Marbán, Eduardo, Cho, Hee Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297875/
https://www.ncbi.nlm.nih.gov/pubmed/25533636
http://dx.doi.org/10.1016/j.stemcr.2014.11.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297875/
https://www.ncbi.nlm.nih.gov/pubmed/25533636
http://dx.doi.org/10.1016/j.stemcr.2014.11.004

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