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Cytoplasmic hybrid (cybrid) cell lines as a practical model for mitochondriopathies

Cytoplasmic hybrid (cybrid) cell lines can incorporate human subject mitochondria and perpetuate its mitochondrial DNA (mtDNA)-encoded components. Since the nuclear background of different cybrid lines can be kept constant, this technique allows investigators to study the influence of mtDNA on cell...

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Detalles Bibliográficos
Autores principales: Wilkins, Heather M., Carl, Steven M., Swerdlow, Russell H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297942/
https://www.ncbi.nlm.nih.gov/pubmed/25460729
http://dx.doi.org/10.1016/j.redox.2014.03.006