Progressive glucose stimulation of islet beta cells reveals a transition from segregated to integrated modular functional connectivity patterns

Collective beta cell activity in islets of Langerhans is critical for the supply of insulin within an organism. Even though individual beta cells are intrinsically heterogeneous, the presence of intercellular coupling mechanisms ensures coordinated activity and a well-regulated exocytosis of insulin...

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Detalles Bibliográficos
Autores principales: Markovič, Rene, Stožer, Andraž, Gosak, Marko, Dolenšek, Jurij, Marhl, Marko, Rupnik, Marjan Slak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297961/
https://www.ncbi.nlm.nih.gov/pubmed/25598507
http://dx.doi.org/10.1038/srep07845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297961/
https://www.ncbi.nlm.nih.gov/pubmed/25598507
http://dx.doi.org/10.1038/srep07845

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