Systems pharmacology of mifepristone (RU486) reveals its 47 hub targets and network: Comprehensive analysis and pharmacological focus on FAK-Src-Paxillin complex

Mifepristone (RU486), a synthetic steroid compound used as an abortifacient drug, has received considerable attention to its anticancer activity recently. To explore the possibility of using mifepristone as a cancer metastasis chemopreventive, we performed a systems pharmacology analysis of mifepris...

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Detalles Bibliográficos
Autores principales: Yu, Suhong, Yang, Xingtian, Zhu, Yewei, Xie, Fangwei, Lu, Yusheng, Yu, Ting, Yan, Cuicui, Shao, Jingwei, Gao, Yu, Mo, Fan, Cai, Guoneng, Sinko, Patrick J., Jia, Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297966/
https://www.ncbi.nlm.nih.gov/pubmed/25597938
http://dx.doi.org/10.1038/srep07830

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297966/
https://www.ncbi.nlm.nih.gov/pubmed/25597938
http://dx.doi.org/10.1038/srep07830

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