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CW-EPR studies revealed different motional properties and oligomeric states of the integrin β(1a) transmembrane domain in detergent micelles or liposomes

Integrins are heterodimeric membrane proteins that regulate essential processes: cell migration, cell growth, extracellular matrix assembly and tumor metastasis. Each integrin α or β subunit contains a large extracellular domain, a single transmembrane (TM) domain, and a short cytoplasmic tail. The...

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Detalles Bibliográficos
Autores principales: Yu, Lu, Wang, Wei, Ling, Shenglong, Liu, Sanling, Xiao, Liang, Xin, Yanlong, Lai, Chaohua, Xiong, Ying, Zhang, Longhua, Tian, Changlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297981/
https://www.ncbi.nlm.nih.gov/pubmed/25597475
http://dx.doi.org/10.1038/srep07848