Evolutionary and structural annotation of disease-associated mutations in human aminoacyl-tRNA synthetases

BACKGROUND: Mutation(s) in proteins are a natural byproduct of evolution but can also cause serious diseases. Aminoacyl-tRNA synthetases (aaRSs) are indispensable components of all cellular protein translational machineries, and in humans they drive translation in both cytoplasm and mitochondria. Mu...

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Detalles Bibliográficos
Autores principales: Datt, Manish, Sharma, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298046/
https://www.ncbi.nlm.nih.gov/pubmed/25476837
http://dx.doi.org/10.1186/1471-2164-15-1063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298046/
https://www.ncbi.nlm.nih.gov/pubmed/25476837
http://dx.doi.org/10.1186/1471-2164-15-1063

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