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Comparison of DNA methylation profiles in human fetal and adult red blood cell progenitors

BACKGROUND: DNA methylation is an epigenetic modification that plays an important role during mammalian development. Around birth in humans, the main site of red blood cell production moves from the fetal liver to the bone marrow. DNA methylation changes at the β-globin locus and a switch from fetal...

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Detalles Bibliográficos
Autores principales: Lessard, Samuel, Beaudoin, Mélissa, Benkirane, Karim, Lettre, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298057/
https://www.ncbi.nlm.nih.gov/pubmed/25606059
http://dx.doi.org/10.1186/s13073-014-0122-2