UDP-glucose dehydrogenase modulates proteoglycan synthesis in articular chondrocytes: its possible involvement and regulation in osteoarthritis

INTRODUCTION: The objective of this study was to investigate the possible role of UDP-glucose dehydrogenase (UGDH) in osteoarthritis (OA) and uncover whether, furthermore how interleukin-1beta (IL-1β) affects UGDH gene expression. METHODS: UGDH specific siRNAs were applied to determine the role of U...

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Detalles Bibliográficos
Autores principales: Wen, Yinxian, Li, Jing, Wang, Linlong, Tie, Kai, Magdalou, Jacques, Chen, Liaobin, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298080/
https://www.ncbi.nlm.nih.gov/pubmed/25465897
http://dx.doi.org/10.1186/s13075-014-0484-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298080/
https://www.ncbi.nlm.nih.gov/pubmed/25465897
http://dx.doi.org/10.1186/s13075-014-0484-2

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