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Evaluation of de novo transcriptome assemblies from RNA-Seq data

De novo RNA-Seq assembly facilitates the study of transcriptomes for species without sequenced genomes, but it is challenging to select the most accurate assembly in this context. To address this challenge, we developed a model-based score, RSEM-EVAL, for evaluating assemblies when the ground truth...

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Detalles Bibliográficos
Autores principales: Li, Bo, Fillmore, Nathanael, Bai, Yongsheng, Collins, Mike, Thomson, James A, Stewart, Ron, Dewey, Colin N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298084/
https://www.ncbi.nlm.nih.gov/pubmed/25608678
http://dx.doi.org/10.1186/s13059-014-0553-5