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Microinjection of specific anti-IMPDH2 antibodies induces disassembly of cytoplasmic rods/rings that are primarily stationary and stable structures

BACKGROUND: Our laboratory previously reported interesting rods 3–10 μm long and rings 2–5 μm diameter (RR) in the cytoplasm of mammalian cells. Experimental evidence show that both inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) and cytidine triphosphate synthetase (CTPS) are components of R...

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Detalles Bibliográficos
Autores principales: Keppeke, Gerson Dierley, Andrade, Luís Eduardo C, Grieshaber, Scott S, Chan, Edward K L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298086/
https://www.ncbi.nlm.nih.gov/pubmed/25601894
http://dx.doi.org/10.1186/2045-3701-5-1