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The transcription factor Nerfin-1 prevents reversion of neurons into neural stem cells

Cellular dedifferentiation is the regression of a cell from a specialized state to a more multipotent state and is implicated in cancer. However, the transcriptional network that prevents differentiated cells from reacquiring stem cell fate is so far unclear. Neuroblasts (NBs), the Drosophila neural...

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Detalles Bibliográficos
Autores principales: Froldi, Francesca, Szuperak, Milan, Weng, Chen-Fang, Shi, Wei, Papenfuss, Anthony T., Cheng, Louise Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298133/
https://www.ncbi.nlm.nih.gov/pubmed/25593306
http://dx.doi.org/10.1101/gad.250282.114