Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination

How chromatin shapes pathways that promote genome–epigenome integrity in response to DNA damage is an issue of crucial importance. We report that human bromodomain (BRD)-containing proteins, the primary “readers” of acetylated chromatin, are vital for the DNA damage response (DDR). We discovered tha...

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Detalles Bibliográficos
Autores principales: Gong, Fade, Chiu, Li-Ya, Cox, Ben, Aymard, François, Clouaire, Thomas, Leung, Justin W., Cammarata, Michael, Perez, Mercedes, Agarwal, Poonam, Brodbelt, Jennifer S., Legube, Gaëlle, Miller, Kyle M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298138/
https://www.ncbi.nlm.nih.gov/pubmed/25593309
http://dx.doi.org/10.1101/gad.252189.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298138/
https://www.ncbi.nlm.nih.gov/pubmed/25593309
http://dx.doi.org/10.1101/gad.252189.114

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