Ablation of insulin-producing cells prevents obesity but not premature mortality caused by a high-sugar diet in Drosophila

Ageing can be modulated by genetic as well as nutritional interventions. In female Drosophila melanogaster, lifespan is maximized at intermediate concentrations of sucrose as the carbohydrate source, and yeast as the protein source. Dampening the signal through the insulin/IGF signalling (IIS) pathw...

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Detalles Bibliográficos
Autores principales: Al Saud, Sara Naif, Summerfield, Adam C., Alic, Nazif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298201/
https://www.ncbi.nlm.nih.gov/pubmed/25520354
http://dx.doi.org/10.1098/rspb.2014.1720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298201/
https://www.ncbi.nlm.nih.gov/pubmed/25520354
http://dx.doi.org/10.1098/rspb.2014.1720

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