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Ablation of insulin-producing cells prevents obesity but not premature mortality caused by a high-sugar diet in Drosophila
Ageing can be modulated by genetic as well as nutritional interventions. In female Drosophila melanogaster, lifespan is maximized at intermediate concentrations of sucrose as the carbohydrate source, and yeast as the protein source. Dampening the signal through the insulin/IGF signalling (IIS) pathw...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298201/ https://www.ncbi.nlm.nih.gov/pubmed/25520354 http://dx.doi.org/10.1098/rspb.2014.1720 |