Unliganded Thyroid Hormone Receptor α Regulates Developmental Timing via Gene Repression in Xenopus tropicalis

Thyroid hormone (TH) receptor (TR) expression begins early in development in all vertebrates when circulating TH levels are absent or minimal, yet few developmental roles for unliganded TRs have been established. Unliganded TRs are expected to repress TH-response genes, increase tissue responsivity...

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Detalles Bibliográficos
Autores principales: Choi, Jinyoung, Suzuki, Ken-ichi T., Sakuma, Tetsushi, Shewade, Leena, Yamamoto, Takashi, Buchholz, Daniel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2015
Materias:
Thyroid-TRH-TSH
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298327/
https://www.ncbi.nlm.nih.gov/pubmed/25456067
http://dx.doi.org/10.1210/en.2014-1554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298327/
https://www.ncbi.nlm.nih.gov/pubmed/25456067
http://dx.doi.org/10.1210/en.2014-1554

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