Characterization of the host–guest complex of a curcumin analog with β-cyclodextrin and β-cyclodextrin–gemini surfactant and evaluation of its anticancer activity

BACKGROUND: Curcumin analogs, including the novel compound NC 2067, are potent cytotoxic agents that suffer from poor solubility, and hence, low bioavailability. Cyclodextrin-based carriers can be used to encapsulate such agents. In order to understand the interaction between the two molecules, the...

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Detalles Bibliográficos
Autores principales: Poorghorban, Masoomeh, Das, Umashankar, Alaidi, Osama, Chitanda, Jackson M, Michel, Deborah, Dimmock, Jonathan, Verrall, Ronald, Grochulski, Pawel, Badea, Ildiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298337/
https://www.ncbi.nlm.nih.gov/pubmed/25609956
http://dx.doi.org/10.2147/IJN.S70828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298337/
https://www.ncbi.nlm.nih.gov/pubmed/25609956
http://dx.doi.org/10.2147/IJN.S70828

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