HMG-CoA reductase inhibitory activity and phytocomponent investigation of Basella alba leaf extract as a treatment for hypercholesterolemia

The enzyme 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase is the key enzyme of the mevalonate pathway that produces cholesterol. Inhibition of HMG-CoA reductase reduces cholesterol biosynthesis in the liver. Synthetic drugs, statins, are commonly used for the treatment of hypercholestero...

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Detalles Bibliográficos
Autores principales: Baskaran, Gunasekaran, Salvamani, Shamala, Ahmad, Siti Aqlima, Shaharuddin, Noor Azmi, Pattiram, Parveen Devi, Shukor, Mohd Yunus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298350/
https://www.ncbi.nlm.nih.gov/pubmed/25609924
http://dx.doi.org/10.2147/DDDT.S75056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298350/
https://www.ncbi.nlm.nih.gov/pubmed/25609924
http://dx.doi.org/10.2147/DDDT.S75056

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