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HMG-CoA reductase inhibitory activity and phytocomponent investigation of Basella alba leaf extract as a treatment for hypercholesterolemia

The enzyme 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase is the key enzyme of the mevalonate pathway that produces cholesterol. Inhibition of HMG-CoA reductase reduces cholesterol biosynthesis in the liver. Synthetic drugs, statins, are commonly used for the treatment of hypercholestero...

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Detalles Bibliográficos
Autores principales:	Baskaran, Gunasekaran, Salvamani, Shamala, Ahmad, Siti Aqlima, Shaharuddin, Noor Azmi, Pattiram, Parveen Devi, Shukor, Mohd Yunus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298350/ https://www.ncbi.nlm.nih.gov/pubmed/25609924 http://dx.doi.org/10.2147/DDDT.S75056

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