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The suppression of ghrelin signaling mitigates age-associated thermogenic impairment

Aging is associated with severe thermogenic impairment, which contributes to obesity and diabetes in aging. We previously reported that ablation of the ghrelin receptor, growth hormone secretagogue receptor (GHS-R), attenuates age-associated obesity and insulin resistance. Ghrelin and obestatin are...

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Detalles Bibliográficos
Autores principales: Lin, Ligen, Lee, Jong Han, Bongmba, Odelia Y. N., Ma, Xiaojun, Zhu, Xiongwei, Sheikh-Hamad, David, Sun, Yuxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298363/
https://www.ncbi.nlm.nih.gov/pubmed/25543537