Downregulation of proapoptotic Bim augments IL-2-independent T-cell transformation by human T-cell leukemia virus type-1 Tax

Human T-cell leukemia virus type 1 (HTLV-1), an etiological agent of adult T-cell leukemia, immortalizes and transforms primary human T cells in vitro in both an interleukin (IL)-2-dependent and IL-2-independent manner. Expression of the HTLV-1 oncoprotein Tax transforms the growth of the mouse T-ce...

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Detalles Bibliográficos
Autores principales: Higuchi, Masaya, Takahashi, Masahiko, Tanaka, Yuetsu, Fujii, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298387/
https://www.ncbi.nlm.nih.gov/pubmed/25175936
http://dx.doi.org/10.1002/cam4.329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298387/
https://www.ncbi.nlm.nih.gov/pubmed/25175936
http://dx.doi.org/10.1002/cam4.329

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