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T-bet regulates differentiation of forkhead box protein 3(+) regulatory T cells in programmed cell death-1-deficient mice
Programmed cell death-1 (PD-1) plays an important role in peripheral T cell tolerance, but whether or not it affects the differentiation of helper T cell subsets remains elusive. Here we describe the importance of PD-1 in the control of T helper type 1 (Th1) cell activation and development of forkhe...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298397/ https://www.ncbi.nlm.nih.gov/pubmed/25219397 http://dx.doi.org/10.1111/cei.12455 |