T-bet regulates differentiation of forkhead box protein 3(+) regulatory T cells in programmed cell death-1-deficient mice

Programmed cell death-1 (PD-1) plays an important role in peripheral T cell tolerance, but whether or not it affects the differentiation of helper T cell subsets remains elusive. Here we describe the importance of PD-1 in the control of T helper type 1 (Th1) cell activation and development of forkhe...

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Detalles Bibliográficos
Autores principales: Tahara, M, Kondo, Y, Yokosawa, M, Tsuboi, H, Takahashi, S, Shibayama, S, Matsumoto, I, Sumida, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298397/
https://www.ncbi.nlm.nih.gov/pubmed/25219397
http://dx.doi.org/10.1111/cei.12455

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