Molecular and cellular function of the proprotein convertase subtilisin/kexin type 9 (PCSK9)

The proprotein convertase subtilisin/kexin type 9 (PCSK9) has emerged as a promising treatment target to lower serum cholesterol, a major risk factor of cardiovascular diseases. Gain-of-function mutations of PCSK9 are associated with hypercholesterolemia and increased risk of cardiovascular events....

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Detalles Bibliográficos
Autores principales: Schulz, Rainer, Schlüter, Klaus-Dieter, Laufs, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Invited Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298671/
https://www.ncbi.nlm.nih.gov/pubmed/25600226
http://dx.doi.org/10.1007/s00395-015-0463-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298671/
https://www.ncbi.nlm.nih.gov/pubmed/25600226
http://dx.doi.org/10.1007/s00395-015-0463-z

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