Mannose 6 phosphorylation of lysosomal enzymes controls B cell functions

Antigen processing and presentation and cytotoxic targeting depend on the activities of several lysosomal enzymes that require mannose 6-phosphate (M6P) sorting signals for efficient intracellular transport and localization. In this paper, we show that mice deficient in the formation of M6P residues...

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Detalles Bibliográficos
Autores principales: Otomo, Takanobu, Schweizer, Michaela, Kollmann, Katrin, Schumacher, Valéa, Muschol, Nicole, Tolosa, Eva, Mittrücker, Hans-Willi, Braulke, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298682/
https://www.ncbi.nlm.nih.gov/pubmed/25601403
http://dx.doi.org/10.1083/jcb.201407077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298682/
https://www.ncbi.nlm.nih.gov/pubmed/25601403
http://dx.doi.org/10.1083/jcb.201407077

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