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Multiple assembly mechanisms anchor the KMN spindle checkpoint platform at human mitotic kinetochores
During mitosis, the spindle checkpoint senses kinetochores not properly attached to spindle microtubules and prevents precocious sister-chromatid separation and aneuploidy. The constitutive centromere-associated network (CCAN) at inner kinetochores anchors the KMN network consisting of Knl1, the Mis...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298689/ https://www.ncbi.nlm.nih.gov/pubmed/25601404 http://dx.doi.org/10.1083/jcb.201407074 |