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Multiple assembly mechanisms anchor the KMN spindle checkpoint platform at human mitotic kinetochores

During mitosis, the spindle checkpoint senses kinetochores not properly attached to spindle microtubules and prevents precocious sister-chromatid separation and aneuploidy. The constitutive centromere-associated network (CCAN) at inner kinetochores anchors the KMN network consisting of Knl1, the Mis...

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Detalles Bibliográficos
Autores principales: Kim, Soonjoung, Yu, Hongtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298689/
https://www.ncbi.nlm.nih.gov/pubmed/25601404
http://dx.doi.org/10.1083/jcb.201407074