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Functional Loop Dynamics of the Streptavidin-Biotin Complex

Accelerated molecular dynamics (aMD) simulation is employed to study the functional dynamics of the flexible loop(3-4) in the strong-binding streptavidin-biotin complex system. Conventional molecular (cMD) simulation is also performed for comparison. The present study reveals the following important...

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Detalles Bibliográficos
Autores principales: Song, Jianing, Li, Yongle, Ji, Changge, Zhang, John Z. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298722/
https://www.ncbi.nlm.nih.gov/pubmed/25601277
http://dx.doi.org/10.1038/srep07906