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Simultaneous impairment of mitochondrial fission and fusion reduces mitophagy and shortens replicative lifespan
Aging of biological systems is accompanied by degeneration of mitochondrial functions. Different pathways are active to counteract the processes which lead to mitochondrial dysfunction. Mitochondrial dynamics, the fission and fusion of mitochondria, is one of these quality control pathways. Mitophag...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298727/ https://www.ncbi.nlm.nih.gov/pubmed/25601284 http://dx.doi.org/10.1038/srep07885 |