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Simultaneous impairment of mitochondrial fission and fusion reduces mitophagy and shortens replicative lifespan

Aging of biological systems is accompanied by degeneration of mitochondrial functions. Different pathways are active to counteract the processes which lead to mitochondrial dysfunction. Mitochondrial dynamics, the fission and fusion of mitochondria, is one of these quality control pathways. Mitophag...

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Detalles Bibliográficos
Autores principales:	Bernhardt, Dominik, Müller, Matthias, Reichert, Andreas S., Osiewacz, Heinz D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298727/ https://www.ncbi.nlm.nih.gov/pubmed/25601284 http://dx.doi.org/10.1038/srep07885

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