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siRNA induces gelsolin gene transcription activation in human esophageal cancer cell

Recent studies show that targeting gene promoter or 3′ terminal regions of mRNA with siRNA induces target gene transcription. However, the ability of exon-targeting siRNA to affect transcription has yet to be demonstrated. We designed and synthesized siRNA against various exons in the gelsolin gene...

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Detalles Bibliográficos
Autores principales: Huang, Guo-Wei, Liao, Lian-Di, Li, En-Min, Xu, Li-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298738/
https://www.ncbi.nlm.nih.gov/pubmed/25600697
http://dx.doi.org/10.1038/srep07901