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siRNA induces gelsolin gene transcription activation in human esophageal cancer cell
Recent studies show that targeting gene promoter or 3′ terminal regions of mRNA with siRNA induces target gene transcription. However, the ability of exon-targeting siRNA to affect transcription has yet to be demonstrated. We designed and synthesized siRNA against various exons in the gelsolin gene...
Autores principales: | Huang, Guo-Wei, Liao, Lian-Di, Li, En-Min, Xu, Li-Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298738/ https://www.ncbi.nlm.nih.gov/pubmed/25600697 http://dx.doi.org/10.1038/srep07901 |
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