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Loss of APD1 in Yeast Confers Hydroxyurea Sensitivity Suppressed by Yap1p Transcription Factor

Ferredoxins are iron-sulfur proteins that play important roles in electron transport and redox homeostasis. Yeast Apd1p is a novel member of the family of thioredoxin-like ferredoxins. In this study, we characterized the hydroxyurea (HU)-hypersensitive phenotype of apd1Δ cells. HU is an inhibitor of...

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Detalles Bibliográficos
Autores principales: Tang, Hei-Man Vincent, Pan, Kewu, Kong, Ka-Yiu Edwin, Hu, Ligang, Chan, Ling-Chim, Siu, Kam-Leung, Sun, Hongzhe, Wong, Chi-Ming, Jin, Dong-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298746/
https://www.ncbi.nlm.nih.gov/pubmed/25600293
http://dx.doi.org/10.1038/srep07897