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Mineralocorticoid receptor signaling reduces numbers of circulating human naïve T cells and increases their CD62L, CCR7, and CXCR4 expression

The role of mineralocorticoid receptors (MRs) in human T-cell migration is not yet understood. We have recently shown that the MR antagonist spironolactone selectively increases the numbers of circulating naïve and central memory T cells during early sleep, which is the time period in the 24 h cycle...

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Detalles Bibliográficos
Autores principales: Besedovsky, Luciana, Linz, Barbara, Born, Jan, Lange, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298762/
https://www.ncbi.nlm.nih.gov/pubmed/24595810
http://dx.doi.org/10.1002/eji.201344265