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A novel immunocompetent murine model for replicating oncolytic adenoviral therapy

Oncolytic adenoviruses are under investigation as a promising novel strategy for cancer immunotherapeutics. Unfortunately, there is no immunocompetent mouse cancer model to test oncolytic adenovirus because murine cancer cells are generally unable to produce infectious viral progeny from human adeno...

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Detalles Bibliográficos
Autores principales: Zhang, L, Hedjran, F, Larson, C, Perez, G L, Reid, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298785/
https://www.ncbi.nlm.nih.gov/pubmed/25525035
http://dx.doi.org/10.1038/cgt.2014.64