MicroRNA-519a is a novel oncomir conferring tamoxifen resistance by targeting a network of tumour-suppressor genes in ER+ breast cancer

Tamoxifen is an endocrine therapy which is administered to up to 70% of all breast cancer patients with oestrogen receptor alpha (ERα) expression. Despite the initial response, most patients eventually acquire resistance to the drug. MicroRNAs (miRNAs) are a class of small non-coding RNAs which have...

Descripción completa

Detalles Bibliográficos
Autores principales: Ward, Aoife, Shukla, Kirti, Balwierz, Aleksandra, Soons, Zita, König, Rainer, Sahin, Özgür, Wiemann, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd. 2014
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298809/
https://www.ncbi.nlm.nih.gov/pubmed/24752803
http://dx.doi.org/10.1002/path.4363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298809/
https://www.ncbi.nlm.nih.gov/pubmed/24752803
http://dx.doi.org/10.1002/path.4363

Ejemplares similares