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Molecular regulation of the expression of leptin by hypoxia in human coronary artery smooth muscle cells
BACKGROUND: Leptin, produced mainly by white adipose tissue, is a hormone that promotes vascular smooth muscle cell (VSMC) migration and proliferation, a process involved in the pathophysiology of atherosclerosis. Leptin expression in human coronary artery smooth cell (HCASMC) is induced by hypoxia....
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298872/ https://www.ncbi.nlm.nih.gov/pubmed/25573199 http://dx.doi.org/10.1186/s12929-014-0109-8 |