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Aminoguanidine partially prevents the reduction in liver pyruvate kinase activity in diabetic rats

BACKGROUND: Low molecular weight aldehydes and carbonyl compounds which are derived from glucose metabolism are prevalent in diabetic plasma. These compounds react to amino groups of Lys and Arg and lead to the formation of advanced glycation end products (AGEs). This modification changes the functi...

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Detalles Bibliográficos
Autores principales: Majd, Alimohammad Amiri, Goodarzi, Mohammad Taghi, Hassanzadeh, Taghi, Tavilani, Heidar, Karimi, Jamshid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298874/
https://www.ncbi.nlm.nih.gov/pubmed/25625099
http://dx.doi.org/10.4103/2277-9175.148233