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Genes suppressed by DNA methylation in non-small cell lung cancer reveal the epigenetics of epithelial–mesenchymal transition

BACKGROUND: DNA methylation is associated with aberrant gene expression in cancer, and has been shown to correlate with therapeutic response and disease prognosis in some types of cancer. We sought to investigate the biological significance of DNA methylation in lung cancer. RESULTS: We integrated t...

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Detalles Bibliográficos
Autores principales: Lin, Steven H, Wang, Jing, Saintigny, Pierre, Wu, Chia-Chin, Giri, Uma, Zhang, Jing, Menju, Toshi, Diao, Lixia, Byers, Lauren, Weinstein, John N, Coombes, Kevin R, Girard, Luc, Komaki, Ritsuko, Wistuba, Ignacio I, Date, Hiroshi, Minna, John D, Heymach, John V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298954/
https://www.ncbi.nlm.nih.gov/pubmed/25486910
http://dx.doi.org/10.1186/1471-2164-15-1079