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Protein expression, characterization and activity comparisons of wild type and mutant DUSP5 proteins

BACKGROUND: The mitogen-activated protein kinases (MAPKs) pathway is critical for cellular signaling, and proteins such as phosphatases that regulate this pathway are important for normal tissue development. Based on our previous work on dual specificity phosphatase-5 (DUSP5), and its role in embryo...

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Detalles Bibliográficos
Autores principales: Nayak, Jaladhi, Gastonguay, Adam J, Talipov, Marat R, Vakeel, Padmanabhan, Span, Elise A, Kalous, Kelsey S, Kutty, Raman G, Jensen, Davin R, Pokkuluri, Phani Raj, Sem, Daniel S, Rathore, Rajendra, Ramchandran, Ramani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299175/
https://www.ncbi.nlm.nih.gov/pubmed/25519881
http://dx.doi.org/10.1186/s12858-014-0027-0