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Precise and efficient genome editing in zebrafish using the CRISPR/Cas9 system
The introduction of engineered site-specific DNA endonucleases has brought precise genome editing in many model organisms and human cells into the realm of possibility. In zebrafish, loss-of-function alleles have been successfully produced; however, germ line transmission of functional targeted knoc...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299274/ https://www.ncbi.nlm.nih.gov/pubmed/25411213 http://dx.doi.org/10.1242/dev.115584 |