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Glutamatergic synaptic plasticity in the mesocorticolimbic system in addiction

Addictive drugs remodel the brain’s reward circuitry, the mesocorticolimbic dopamine (DA) system, by inducing widespread adaptations of glutamatergic synapses. This drug-induced synaptic plasticity is thought to contribute to both the development and the persistence of addiction. This review highlig...

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Detalles Bibliográficos
Autores principales: van Huijstee, Aile N., Mansvelder, Huibert D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299443/
https://www.ncbi.nlm.nih.gov/pubmed/25653591
http://dx.doi.org/10.3389/fncel.2014.00466