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Mitochondrial protection by the mixed muscarinic/σ(1) ligand ANAVEX2-73, a tetrahydrofuran derivative, in Aβ(25–35) peptide-injected mice, a nontransgenic Alzheimer’s disease model
Alzheimer’s disease (AD), the most prevalent dementia in the elderly, is characterized by progressive synaptic and neuronal loss. Mitochondrial dysfunctions have been consistently reported as an early event in AD and appear before Aβ deposition and memory decline. In order to define a new neuroprote...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299448/ https://www.ncbi.nlm.nih.gov/pubmed/25653589 http://dx.doi.org/10.3389/fncel.2014.00463 |