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The Good, the Bad, and the Ugly: in search of gold standards for assessing functional genetic screen quality
Variable screen quality, off-target effects, and unclear false discovery rates often hamper large-scale functional genomic screens in mammalian cells. Hart et al (2014) introduce gold standard reference sets of essential and non-essential genes, aiming at standardizing the analysis of genome-wide sc...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299495/ https://www.ncbi.nlm.nih.gov/pubmed/24987117 http://dx.doi.org/10.15252/msb.20145372 |