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Pharmacokinetics Interaction between Imatinib and Genistein in Rats

The objective of this work was to investigate the effect of orally administered genistein on the pharmacokinetics of imatinib and N-desmethyl imatinib in rats. Twenty-five healthy male SD (Sprague-Dawley) rats were randomly divided into five groups: A group (control group), B group (multiple dose of...

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Detalles Bibliográficos
Autores principales: Wang, Zhe, Wang, Li, Xia, Meng-ming, Sun, Wei, Huang, Cheng-ke, Cui, Xiao, Hu, Guo-xin, Lian, Qing-quan, Wang, Zeng-shou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299555/
https://www.ncbi.nlm.nih.gov/pubmed/25629045
http://dx.doi.org/10.1155/2015/368976