Distribution of allelic and genotypic frequencies of NAT2 and CYP2E1 variants in Moroccan population

BACKGROUND: Several pathogenesis and genetic factors influence predisposition to antituberculosis drug-induced hepatotoxicity (ATDH) especially for isoniazid (INH). However, the major susceptibility genes for ATDH are N-acetyltransferase 2 (NAT2) and cytochrome P450 2E1 (CYP2E1). NAT2 gene determine...

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Detalles Bibliográficos
Autores principales: Guaoua, Soukaina, Ratbi, Ilham, Laarabi, Fatima Zahra, Elalaoui, Siham Chafai, Jaouad, Imane Cherkaoui, Barkat, Amina, Sefiani, Abdelaziz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299568/
https://www.ncbi.nlm.nih.gov/pubmed/25544508
http://dx.doi.org/10.1186/s12863-014-0156-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299568/
https://www.ncbi.nlm.nih.gov/pubmed/25544508
http://dx.doi.org/10.1186/s12863-014-0156-x

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