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Metabolic engineering of the fungal D-galacturonate pathway for L-ascorbic acid production

BACKGROUND: Synthetic L-ascorbic acid (vitamin C) is widely used as a preservative and nutrient in food and pharmaceutical industries. In the current production method, D-glucose is converted to L-ascorbic acid via several biochemical and chemical steps. The main source of L-ascorbic acid in human n...

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Detalles Bibliográficos
Autores principales: Kuivanen, Joosu, Penttilä, Merja, Richard, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299797/
https://www.ncbi.nlm.nih.gov/pubmed/25566698
http://dx.doi.org/10.1186/s12934-014-0184-2