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Expression of the functional recombinant human glycosyltransferase GalNAcT2 in Escherichia coli
BACKGROUND: Recombinant protein-based therapeutics have become indispensable for the treatment of many diseases. They are produced using well-established expression systems based on bacteria, yeast, insect and mammalian cells. The majority of therapeutic proteins are glycoproteins and therefore the...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299809/ https://www.ncbi.nlm.nih.gov/pubmed/25582753 http://dx.doi.org/10.1186/s12934-014-0186-0 |