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Increased cortical curvature reflects white matter atrophy in individual patients with early multiple sclerosis

OBJECTIVE: White matter atrophy occurs independently of lesions in multiple sclerosis. In contrast to lesion detection, the quantitative assessment of white matter atrophy in individual patients has been regarded as a major challenge. We therefore tested the hypothesis that white matter atrophy (WMA...

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Detalles Bibliográficos
Autores principales: Deppe, Michael, Marinell, Jasmin, Krämer, Julia, Duning, Thomas, Ruck, Tobias, Simon, Ole J., Zipp, Frauke, Wiendl, Heinz, Meuth, Sven G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299934/
https://www.ncbi.nlm.nih.gov/pubmed/25610761
http://dx.doi.org/10.1016/j.nicl.2014.02.012