Annexin A2 promotes phagophore assembly by enhancing Atg16L(+) vesicle biogenesis and homotypic fusion

Plasma membrane budding of Atg-16L-positive vesicles represents a very early event in the generation of the phagophore and in the process of macroautophagy. Here we show that the membrane curvature-inducing protein annexin A2 contributes to the formation of these vesicles and their fusion to form ph...

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Detalles Bibliográficos
Autores principales: Morozova, Kateryna, Sidhar, Sunandini, Zolla, Valerio, Clement, Cristina C., Scharf, Brian, Verzani, Zoe, Diaz, Antonio, Larocca, Jorge N., Hajjar, Katherine A., Cuervo, Ana Maria, Santambrogio, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299943/
https://www.ncbi.nlm.nih.gov/pubmed/25597631
http://dx.doi.org/10.1038/ncomms6856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299943/
https://www.ncbi.nlm.nih.gov/pubmed/25597631
http://dx.doi.org/10.1038/ncomms6856

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