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Differential localization and potency of manganese porphyrin superoxide dismutase-mimicking compounds in Saccharomyces cerevisiae

Cationic Mn(III) porphyrin complexes based on MnTM-2-PyP are among the most promising superoxide dismutase (SOD) mimicking compounds being considered as potential anti-inflammatory drugs. We studied four of these active compounds in the yeast Saccharomyces cerevisiae, MnTM-2-PyP, MnTE-2-PyP, MnTnHex...

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Detalles Bibliográficos
Autores principales: Li, Alice Ma, Martins, Jake, Tovmasyan, Artak, Valentine, Joan S., Batinic-Haberle, Ines, Spasojevic, Ivan, Gralla, Edith B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299968/
https://www.ncbi.nlm.nih.gov/pubmed/25462059
http://dx.doi.org/10.1016/j.redox.2014.09.003