The highly polymorphic cyclophilin A-binding loop in HIV-1 capsid modulates viral resistance to MxB

BACKGROUND: The human myxovirus-resistance protein B (MxB, also called Mx2) was recently reported to inhibit HIV-1 infection by impeding the nuclear import and integration of viral DNA. However, it is currently unknown whether there exist MxB-resistant HIV-1 strains in the infected individuals. Answ...

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Detalles Bibliográficos
Autores principales: Liu, Zhenlong, Pan, Qinghua, Liang, Zhibin, Qiao, Wentao, Cen, Shan, Liang, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300040/
https://www.ncbi.nlm.nih.gov/pubmed/25571928
http://dx.doi.org/10.1186/s12977-014-0129-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300040/
https://www.ncbi.nlm.nih.gov/pubmed/25571928
http://dx.doi.org/10.1186/s12977-014-0129-1

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